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High Sensitivity Troponin FDA Approved

Rob Orman, MD and Mel Herbert, MD MBBS FAAEM
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02:44
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No me gusta!

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It’s been years in the making and, at long last, a high sensitivity troponin assay has been approved for use in the United States. Is it such a good thing?

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Aaron G. -

We've been using hsTnT (Roche) for the past 5 years or so. The definition of an MI requires a change in TnT over time, so the fact that everyone seems to have a "positive" troponin with this assay is moot. It's also important to remember that this assay is highly *tissue* specific, but has poor *disease* specificity (with a single value; improves with serial values). Locally, we are not 100% convinced on any of the algorithms that have been published. We are working on creating our own but we'll see what happens. The biggest problem is there is no universal definition of a "significant" change for different time intervals.

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High Sensitivity Troponin FDA Approved Full episode audio for MD edition 2:44 min - 2 MB - M4A