Britt gives us a review of the drug treatment for rapid atrial fibrillation, from EM:RAP February 2022.
Won't the CaGluc minimize the dilt. effect on HR?
The calcium preferentially affects smooth muscle over AV node and reduces vasodilation. Having said that the studies were almost all with verapamil anti is not clear if this has much of an effect with diltiazem so most people don't do it.
https://pubmed.ncbi.nlm.nih.gov/15093843/https://www.sciencedirect.com/science/article/abs/pii/S0736467904000265https://escholarship.org/content/qt4mz7j8nd/qt4mz7j8nd_noSplash_f6910f63436ebc6269b53de0cb0c1f5b.pdf?t=nu3toa
Kenneth A. - December 6, 2022 7:08 AM
Won't the CaGluc minimize the dilt. effect on HR?
Mel H. - December 6, 2022 8:17 AM
The calcium preferentially affects smooth muscle over AV node and reduces vasodilation. Having said that the studies were almost all with verapamil anti is not clear if this has much of an effect with diltiazem so most people don't do it.
https://pubmed.ncbi.nlm.nih.gov/15093843/
https://www.sciencedirect.com/science/article/abs/pii/S0736467904000265
https://escholarship.org/content/qt4mz7j8nd/qt4mz7j8nd_noSplash_f6910f63436ebc6269b53de0cb0c1f5b.pdf?t=nu3toa