Classic Paper: ISIS-2

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Do you know why you give aspirin for acute MI? Mel discusses the ISIS-2 paper from 1988 that established this practice.

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Miss Marple -

for people on anticoagulant presenting with chest pain, possibke ACS, Aspirin is still ok to give rigtht? would it matter which anticoagulant? thank you 😊

Miss Marple -

what about people on other NSAIDs e.g. Ibuprofen?

Mel H. -

Yes aspirin is used in addition to other anticoagulants

Justin D. -

I would be interested to know what these 20 papers

Mel H. -

Justin D - I am gathering a list

Devin M. -

So before 1998 were people treating MIs with just Morphine and Prayer?

Mel H. -

Basically yes - and "bedrest" and treatment of arrhythmias

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