In patients with soft tissue infection, the practice of using outpatient IV antibiotics is becoming more commonplace. Vancomycin is one of the most frequently selected agents, but is it being used correctly? Is once a day enough? Bryan Hayes says… no. Most people will clear vancomycin before the 24 hour mark and need to be dosed at least twice daily. But this brings up the larger question- is IV vancomycin the best choice in the first place?
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