September 2019

Abstract 8: Levetiracetam Vs Phenytoin for Status Treatment in Kids (EcLiPSE)

EMA 2019 September29 Chapters

  1. Introduction6:43
  2. Ultra Summary24:34
  3. Rick’s Rants: Our Prices Are Too High17:11
  4. Time To Talk A Little Nerdy: Statistical Significance17:48
  5. Reflections of a Skeptic: EBM Part I20:16
  6. Then And Now: Saline vs. Balanced Solutions Again!19:41
  7. Farewell2:02
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Ian L. -

In July 2019 EM :RAP chapter 3 : Pediatric Status Al Sachetti and others advocate Ketamine IV first line 1-2mg /kg after two doses of nasal midazolam not working to quiet the NMDA receptors before Keppra or Phosphenatoin.
as ketamine acts faster .
So they would go for ketamine IV first after maximal benzodiazepines .
There is the theory oh GABA receptors diminishing and NMDA receptors increasing .
NB Propofol can be extremely dangerous in children particular after "short term "according to Irene Claudius - the terrible Propofol Infusion syndrome .

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