Re: users preferring 2C-B to MDMA because it doesn't deplete serotonin: I believe depletion of serotonin is thought to be a possible mechanism for the "crash"/brief period of depression that people can experience after MDMA use, especially with frequent or repeated use. Not surprising that people might prefer it, if 2C-B has a similar high without that particular adverse effect.
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EMA 2020 OctoberFull episode audio for MD edition194:00 min - 179 MB - M4AEMA 2020 October - All Abstracts PDF386 KB - PDFEMA 2020 October - Individual MP3s157 MB - ZIP
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Joe Colucci - October 1, 2020 5:08 PM
Hi guys,
Re: users preferring 2C-B to MDMA because it doesn't deplete serotonin: I believe depletion of serotonin is thought to be a possible mechanism for the "crash"/brief period of depression that people can experience after MDMA use, especially with frequent or repeated use. Not surprising that people might prefer it, if 2C-B has a similar high without that particular adverse effect.