Tamara - interesting question. From my quick search, there's limited info on IV TXA for hemoptysis (there's also limited evidence for inhaled, of course) Here's a 2017 update in clinical pulmonary medicine: https://journals.lww.com/clinpulm/Abstract/2017/03000/Tranexamic_Acid_for_Hemoptysis___A_Review.4.aspx
None of these studies really tackles the acute bleeder in the ED either
EM:RAP 2019 MarchFull episode audio for MD edition207:41 min - 289 MB - M4AEM:RAP 2019 March German EditionDeutsche90:57 min - 125 MB - MP3EM:RAP 2019 March Aussie EditionAustralian34:56 min - 48 MB - MP3EM:RAP 2019 March Farsi EditionFarsi64:12 min - 88 MB - MP3EM:RAP 2019 March French EditionFrançais22:38 min - 31 MB - MP3EM:RAP 2019 March Spanish EditionEspañol78:59 min - 108 MB - MP3EM:RAP 2019 March Canadian EditionCanadian18:22 min - 25 MB - MP3EMRAP_2019 03 March Board Review Answers_V2135 KB - PDFEMRAP_2019 03 March Board Review Questions_V296 KB - PDFEMRAP 2019 03 March Individual MP3229 MB - ZIPEMRAP_2019_03_March_Individual_Written601 KB - ZIPEMRAP 2019 03 March Spanish Written1 MB - PDFEMRAP 2019 03 March Written Summary434 KB - PDF
Tamara A. - March 2, 2019 10:35 AM
You mentioned that nebulized TXA is not useful, is there a role for IV TXA in massive hemoptysis?
Anand S. - March 2, 2019 11:23 AM
Tamara - interesting question. From my quick search, there's limited info on IV TXA for hemoptysis (there's also limited evidence for inhaled, of course)
Here's a 2017 update in clinical pulmonary medicine: https://journals.lww.com/clinpulm/Abstract/2017/03000/Tranexamic_Acid_for_Hemoptysis___A_Review.4.aspx
None of these studies really tackles the acute bleeder in the ED either
Milton M. - June 19, 2019 8:52 AM
Would anyone else here consider comfort care when massive bleed occurs in known lung cancer patient??