strong work, love the Floyd, and the topic. athough a grain of of sand is tiny, specifics can be helpful. a typical blotter or sugar cube psychedelic dose of LSD is approx 100mcg. usual micro dosing reccs are 3-5mcg, maybe as high as 10. it requires a significant effort to dilute accurately, and as such this can a useful part of the history if you have someone tripping balls in your ED.
Great discussion. Regarding “Avoid the use of haloperidol or similar neuroleptics as these may cause messy interactions with some of the agents used. This is especially true for anticholinergic patients as there is already an anticholinergic component to many of the neuroleptic agents”: Are you still seeing the “B52” cocktail used in unidentified but suspected drug-induced psychosis, and is there concern here for the combined anticholinergic effects of haloperidol and diphenhydramine (excluding whatever additional unidentified anticholinergic drugs may be in one’s system)?
You are correct. Some use the classic B52 cocktail for a very broad group of agitated patients. The anticholinergic aspects of this may interact with some hallucinogens, hence the general desire to use benzodiazepines instead.
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Melinda N. - April 3, 2020 8:57 PM
Ohhh any topic with the beastie boys would be great or the Rolling Stones 😁
Zombiekiller,MD - April 7, 2020 9:32 PM
strong work, love the Floyd, and the topic. athough a grain of of sand is tiny, specifics can be helpful. a typical blotter or sugar cube psychedelic dose of LSD is approx 100mcg. usual micro dosing reccs are 3-5mcg, maybe as high as 10. it requires a significant effort to dilute accurately, and as such this can a useful part of the history if you have someone tripping balls in your ED.
Michael L., M.D. - April 11, 2020 11:28 AM
I was glad to hear a track from Animals. That album is its own pocket universe.
Mary C. - April 16, 2020 1:50 PM
Great discussion. Regarding “Avoid the use of haloperidol or similar neuroleptics as these may cause messy interactions with some of the agents used. This is especially true for anticholinergic patients as there is already an anticholinergic component to many of the neuroleptic agents”: Are you still seeing the “B52” cocktail used in unidentified but suspected drug-induced psychosis, and is there concern here for the combined anticholinergic effects of haloperidol and diphenhydramine (excluding whatever additional unidentified anticholinergic drugs may be in one’s system)?
Daniel M. - April 16, 2020 1:54 PM
Mary,
You are correct. Some use the classic B52 cocktail for a very broad group of agitated patients. The anticholinergic aspects of this may interact with some hallucinogens, hence the general desire to use benzodiazepines instead.
Mary C. - April 17, 2020 8:13 AM
Thank you!
Jimmy S. - June 26, 2020 3:39 AM
Phish. You should do a segment with Phish as the band. I haven't thought of a parallel EM topic yet, but I will think on it.