Fomepizole in Acetaminophen Toxicity

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No me gusta!

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Lee D. -

Any role for addition of glutathione IM in management of Tylenol ingestions?

Sean N. -

Hi Lee,

Thanks for the comment!

Great question! N-acyetylcysteine repletes glutathione, in addition to other actions. This obviates the need for additional glutathione. Early days in acetaminophen poisoning, methionine used to be given then N-acetylcysteine became standard therapy.

Sean

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EM:RAP 2022 September SNACK: Fomepizole in Acetaminophen Toxicity Full episode audio for MD edition 7:52 min - 9 MB - M4A