December 2021

Approach to the Critical Patient and Key Concepts

Ethanol Withdrawal4 Chapters

  1. 2

    Diagnosis and Treatment

  2. 3

    Deep Dive

  3. 4


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No me gusta!

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tom f. -

Nice, Jess and Mel

Will L. -

This question is for Jessica Mason; Mel Herbert; Sean Nordt; and Stuart Swadron regarding the C3 segment on Alcohol Withdrawal.

What kills people in ETOH withdrawal?

I did a recent teaching session w/ nursing staff and residents about pathophys of withdrawal and treatment and I was asked the same question and I couldn't give a crisp answer.

Basically, for agitation and excited state 2/2 downregulation of GABA activity w/ treat w/ phenobarb and/or benzos (and maybe some 2ndary agents). But, by treating agitation and hopefully preventing withdrawal seizures, are we eliminating all-cause mortality?

Of course we're doing further workup and fixing problems as we find them. But we do this for all acutely ill individuals . . . . Which makes me ask: by treating patients for alcohol withdrawal, are we preventing death by treating with benzo/pheno, or are we reducing mortality by doing appropriate workups to prevent other causes of death in this high-risk population?

Doing a lit search on pubmed, corependium and up-to-date I couldn't find a satisfactory answer. Can you folks help me out?

Thanks a lot.

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Ethanol Withdrawal Full episode audio for MD edition 64:41 min - 70 MB - M4AC3 Ethanol Withdrawal MP3 Files 76 MB - ZIP