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We are now in the era of damage control resuscitation: rapid hemorrhage control through early massive transfusion of blood products during hemorrhagic shock.
James C. - April 25, 2017 7:43 AM
Can someone please clarify once and for all, as I feel as though I am being told different things depending on what hospital I am at (my current one doesn't even stock platelets). In the 1:1:1 transfusion, is it ONE UNIT of platelets (a full six pack ) or it is one single pack? (1/6 of a unit).
Mel H. - April 25, 2017 8:14 AM
Directly from the PROPPR study:
"All containers for the 1:1:1 group included 6 U of plasma, 1 dose of platelets (a pool of 6 U on average), and 6 U of RBCs, which were transfused in the following order: platelets first, then alternating RBC and plasma units. The initial and all subsequent odd-numbered containers for the 1:1:2 group included 3 U of plasma, 0 doses of platelets, and 6 U of RBCs, which were transfused in the following order: alternating 2 U of RBCs and 1 U of plasma. The second and all subsequent even-numbered containers included 3 U of plasma, 1 dose of platelets (a pool of 6 U on average), and 6 U of RBCs, which were transfused in the following order: platelets first, then alternating 2 U of RBCs and 1 unit of plasma. Patients with multiple intravenous lines could receive blood products simultaneously, otherwise patients received products sequentially. "
James C. - April 26, 2017 12:09 PM
Maybe they should have called it the 6:6:6 protocol.... not that the 666 protocol name would have caused any worry.
Mel H. - April 26, 2017 12:21 PM
Oh I so going to steal that line!
Matthew J. - April 26, 2017 7:23 AM
Any advice about MTP in peds trauma?