February 2020

The Generalist: Mumps


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Ian L. -

The vaccine is live attenuated so does this pose are risk those older and the immunosuppressed .
What about mumps immunoglobulin then for close contacts ?

Heidi J., MD -

Hi Ian - Here's a reply from Chris Drumm:

It is sad to say but the immune globulin has not been shown to lessen disease severity. The MMRI vaccine is contraindicated if someone has and immunodeficiency (including HIV with low CD4 counts, leukemia/lymphoma, those on systemic immunosuppressive therapy). It does not pose a risk to patients that are older though.
But the immune globulin has been shown to be helpful in the case of measles.

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