Reviews & Perspectives with Dr. Hobart Lee: Colchicine Post MI
Hobart Lee, MD, and Heidi James, MD
Inflammation is thought to be a cause of cardiovascular disease, and new drugs are developed to target this pathophysiology. Tardif et al. decided to see whether colchicine, an old medication with anti-inflammatory properties, might be useful in secondary prevention after myocardial infarction (MI).
Hoby and Heidi note the following:
Efficacy and safety of low-dose colchicine after myocardial infarction. Tardif J-C, Kouz S, Waters DD, et al. N Engl J Med. 2019;381:2497-2505. doi: 10.1056/NEJMoa1912388.
Ian L. - May 2, 2020 12:31 AM
Colchicine is dangerous in overdose in ought not be uses on a very wide basis
Ian L. - May 2, 2020 12:43 AM
Colchicine danger was described by toxicologist Sean Nordt as being badness in "Pumping the Stomach no more " 2018 may em rap .
Heidi J., MD - May 11, 2020 5:32 AM
You're right - Colchicine is certainly not benign and should be prescribed cautiously.
Ian L. - May 18, 2020 1:28 AM
For patients that cannot tolerate statins .