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Vesicular & Bullous Lesions Overview

Gita Pensa, MD and Jessica Mason, MD
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Crunch Time - Skin - Written Summary 298 KB - PDF

Vesicular & Bullous Lesions Overview

Gita Pensa MD and Jessica Mason M

  • Extensive bullae/blistering and oral involvement
    • Hospitalization
    • Possible ICU/Burn unit
  • Bullous Pemphigoid
    • Older people more often affected
    • Chronic process
    • Large tense bullae (flexor, intertriginous)
    • Some mucous membrane involvement
  • Pemphigus vulgaris
    • Compared to Bullous Pemphigoid
      • Higher mortality rate
      • Younger patients
      • Systemic symptoms
      • More bullae
      • More mucous membrane involvement
    • Fatal if untreated
  • Staph Scalded Skin
    • Children
    • Presentation
      • Systemic symptoms
      • First, sunburn-appearance
      • Then, bullae/scalded skin
      • Does not involve mucous membranes
      • May have positive Nikolsky’s sign
    • Lower mortality with proper support
      • Strep scalded skin with GAS does have higher mortality however
  • EM Major
    • Usually ages 10-30
    • Target lesions with some bullae (<10% BSA)
    • Limited oral involvement
    • Systemically not too sick
    • May have positive Nikolsky’s sign
    • Low mortality
  • TEN
    • Usually in adults
    • Often medication related
    • Severe systemic symptoms
    • Significant mucous membrane involvement
    • Positive Nikolsky’s sign
    • High mortality rate (SJS is the milder version)
    • ICU/Burn center care

 

 

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Skin Full episode audio for MD edition 77:36 min - 108 MB - M4ACrunch Time - Skin - Individual MP3 Files 6 MB - ZIPCrunch Time - Skin - Written Summary 298 KB - PDF

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