To perform a sphenopalatine ganglion block, first use a nasal mucosal atomizer with 1-2 ml of liquid lidocaine to anesthetize the nare(s). Next, soak a cotton-tipped applicator in topical anesthetic (e.g. 2% lidocaine), and introduce the applicator under the middle turbinate (horizontally) until you touch the posterior nasopharynx. Leave the applicator in place for 10 minutes before removing. You can perform the procedure unilaterally or bilaterally depending on the distribution of the headache.