I have to disagree on diphenhydramine. While it's not EBM, I've only observed akathisia when I didn't administer diphenhydramine. The akathisia broke with IV diphenhydramine. Akathisia is traumatic for the patient and staff. Diphenhydramine is pretty benign so if it might prevent akisthesia in 8% of patients, that seems worth it
Agree with above. Also, wanted to add that while I have not yet tried intranasal lidocaine for migraine, and am willing to give it a shot, in the interest of fairness to the program, on EMA March 2017 #12, Jerry and cast refute intranasal lidfocaine as effective (in the sense that it does not have lasting effect.
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Dallas H. - November 9, 2017 3:00 PM
I have to disagree on diphenhydramine. While it's not EBM, I've only observed akathisia when I didn't administer diphenhydramine. The akathisia broke with IV diphenhydramine. Akathisia is traumatic for the patient and staff. Diphenhydramine is pretty benign so if it might prevent akisthesia in 8% of patients, that seems worth it
Bill W. - February 10, 2018 9:31 PM
Agree with above. Also, wanted to add that while I have not yet tried intranasal lidocaine for migraine, and am willing to give it a shot, in the interest of fairness to the program, on EMA March 2017 #12, Jerry and cast refute intranasal lidfocaine as effective (in the sense that it does not have lasting effect.