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Hyperemesis Gravidarum

Matt DeLaney MD
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25:50
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Nurses Edition Commentary

Lisa Chavez, RN and Kathy Garvin, RN
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03:25

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EM:RAP January 2018 Written Summary 933 KB - PDF

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Cory B., MD -

A researcher up here in Toronto was able to access industry data on Diclegis (pyridoxine and doxylamine) and his reanalysis of the original "positive" data for this drug shows that it does not work any better than placebo. https://www.ncbi.nlm.nih.gov/pubmed/29342163

Matthew D. -

Yeah it's interesting to see what they did in terms of trying to account for the missing data. I think this shows that Diclegis may work but isn't a wonder drug worth its high price. For a few bucks patients can get the OTC ingredients and see if it helps.

Ian L., Dr -

There is the the BRATT foods banana rice apple sauce toast and tea recommendation by the American College of O and G Dec 2015 and dry toast and crackers in the morning before getting out of bed small frequent meals of the BRATT nutrient group also by Foodwatch : avoid odours that cause nausea dab lavender and peppermint on a handkerchief lie on your side after eating get out of bed slowly and pleasant distractions .Foodwatch Catherine Saxelby October 5 2012 .
Many Governments have advice groups eg UK BabyCentre Advisory Board .

Jeff S -

It's a n of 1, but my wife took quite a bit of zofran during her pregnancy and we have a daughter born with a cleft lip and palate. You can imagine we looked pretty hard for any other potential causes, and found that my wife has a mutation in the gene for MTHFR, which may also be linked. So I get it, it's an "A, B, both, neither" situation. But I can't tell by looking at someone what other risk factors they may have lurking in their genetic code and don't want add any confounders. I don't prescribe it anymore, for what it's worth.

Jonathan G. -

It's interesting the dosing on UpToDate says to "Tablets should be taken as scheduled and not on an as needed basis." This is their dosing recommendation Two tablets at bedtime on day 1 and 2; if symptoms persist, take 1 tablet in morning and 2 tablets at bedtime on day 3; if symptoms persist, may increase to 1 tablet in morning, 1 tablet mid-afternoon, and 2 tablets at bedtime on day 4.

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The Collector Full episode audio for MD edition 263:02 min - 367 MB - M4AEM:RAP 2018 January German Edition Deutsche 96:14 min - 132 MB - MP3EM:RAP 2018 January Canadian Edition Canadian 18:24 min - 25 MB - MP3EM:RAP 2018 January Spanish Edition Español 94:31 min - 130 MB - MP3EM:RAP 2018 January French Edition Français 21:02 min - 29 MB - MP3EM:RAP 2018 January Individual MP3 340 MB - ZIPEM:RAP 2018 January Individual Written 964 KB - ZIPEM:RAP 2018 January Spanish Written 1,019 KB - PDFEMRAP Board Review Answers 2018 01 Jan Vol.18 01 95 KB - PDFEMRAP Board Review Questions 2018 01 Jan Vol.18 01 161 KB - PDFEM:RAP January 2018 Written Summary 933 KB - PDF

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