Start with a free trial account for free content every month. Already a subscriber? Sign in.

The Agent/Antidote Game

Sean Nordt, MD PharmD FAAEM and Stuart Swadron, MD, FRCPC

Playback Speed

No me gusta!

The flash player was unable to start. If you have a flash blocker then try unblocking the flash content - it should be visible below.

Crunch Time EM - Tox - Written Summary 392 KB - PDF

The Agent/Antidote Game

Sean Nordt MD and Stuart Swadron MD

  • Acetaminophen  → N-Acetylcysteine
  • Aspirin  → Sodium bicarb and hemodialysis (HD)
  • Organophosphates  → Atropine, pralidoxime, diazepam (for seizures)
  • Carbamates  → Atropine, diazepam
  • Warfarin  → Vitamin K, PCC
  • Digoxin  → Fab fragments
  • Ethylene glycol →  Fomepizole or ethanol, HD
  • HFl acid  → Calcium, magnesium
  • Isoniazid  → Pyridoxine
  • Methanol  → Fomepizole or ethanol, HD
  • TCAs  → Sodium bicarb
  • Carbon monoxide  → Oxygen and hyperbaric oxygen
  • Beta blocker  → Glucagon, calcium, high-dose insulin, intralipid = controversial
  • CCB  → Calcium, glucagon, high-dose insulin, intralipid = controversial
  • Heavy metals   → Chelators - BAL then calcium disodium EDTA    (lead, mercury, arsenic)
  • Iron  → Chelator deferoxamine
  • Cyanide  → Hydroxocobalamin, sodium nitrate, amyl nitrate, sodium thiosulfate

To join the conversation, you need to subscribe.

Sign up today for full access to all episodes and to join the conversation.

To download files, you need to subscribe.

Sign up today for full access to all episodes.
Tox Full episode audio for MD edition 103:01 min - 143 MB - M4ACrunch Time EM - Tox - Individual MP3 Files 129 MB - ZIPCrunch Time EM - Tox - Written Summary 392 KB - PDF

Choose your Quiz!

More quizzes coming soon.
View All Crunchy Qs